The .32 H&R Magnum was developed primarily as a revolver cartridge; however, it has also become popular in the lever-action rifles such as the Marlin Model 1894 Cowboy.

In developing and firing data in the Marlin rifle, several published loads gave either erratic velocities or stuck bullets in the bore from excessively light powder charges and low pressures, a very dangerous situation. Those loads were eliminated from the accompanying data; only reliable data is listed. Based on these experiences, "starting" loads should not be reduced, especially data containing jacketed bullets.

The 90-grain Hornady lead hollow-base wad-cutter would not feed in the Marlin lever-action rifle and was fired in the single shot mode. The Hornady 90-grain lead SWC bullet fed reliably.

Ammunition for tubular magazine rifles should have a heavy crimp to keep bullets in place when subjected to magazine spring pressure. This likewise aids in obtaining reliable powder ignition and accuracy.